A biopsy involves:

A biopsy is a medical procedure that involves obtaining a sample of tissue to examine it for the presence of disease, most commonly cancer. The process of withdrawing a tissue sample through a needle is known as a needle biopsy or fine-needle aspiration. This method is often less invasive and can be performed with the aid of imaging technology to ensure that the correct area is targeted. This approach allows for less tissue trauma and quicker recovery times compared to more invasive surgical procedures.

In this context, the other methods mentioned, such as using a laser to destroy tumor tissue or utilizing X-rays to remove a tumor, do not align with the standard definition of a biopsy. Additionally, while using a scalpel to remove tissue can be part of a surgical biopsy procedure, it is typically more invasive than the needle biopsy approach and would not be the primary method described in this question. Therefore, the choice indicating the withdrawal of a tissue sample through a needle accurately captures the essence of what a biopsy involves, making it the correct answer.