A moon face and a buffalo hump are symptoms of:

The symptoms of a moon face and a buffalo hump are classic indicators of Cushing's syndrome. Cushing's syndrome occurs when there is an excess of cortisol in the body, which can be due to various factors, including prolonged use of corticosteroid medications or disorders of the adrenal glands or pituitary gland.

The term "moon face" refers to the rounded appearance of the face that develops due to fat redistribution and fluid retention, while the "buffalo hump" describes a fat deposit that forms at the nape of the neck. Both symptoms are a result of the body’s altered metabolism and buildup of fat in particular areas due to elevated cortisol levels. Recognizing these symptoms is crucial for early diagnosis and treatment of Cushing's syndrome, distinguishing it from other conditions like Addison's disease, which presents differently and involves adrenal insufficiency, or myxedema and Grave's disease, which are related to thyroid dysfunction.