What condition is characterized by the degeneration of cartilage in the joints?

Osteoarthritis is characterized by the degeneration of cartilage in the joints, leading to pain, stiffness, and reduced mobility. This condition occurs when the protective cartilage that cushions the ends of the bones wears down over time, often due to age, wear and tear, or injury. As the cartilage deteriorates, bones may rub against each other, resulting in inflammation and discomfort.

In contrast, rheumatoid arthritis is an autoimmune disorder that primarily affects the lining of the joints, causing inflammation rather than direct degradation of cartilage. Gout is a type of inflammatory arthritis caused by the accumulation of uric acid crystals in the joints, leading to intense pain and swelling but not related to the degeneration of cartilage itself. Lupus is another autoimmune condition that can affect various body systems, including joints, but it does not specifically involve cartilage degeneration as a primary characteristic.