What type of infection is Amphotericin B primarily used to treat?

Amphotericin B is primarily used to treat fungal infections, particularly those caused by organisms such as Aspergillus. It is a polyene antifungal medication that works by binding to ergosterol in the fungal cell membrane, leading to increased permeability and cell death. This makes it particularly effective against severe systemic fungal infections, including those caused by Aspergillus species, which can lead to serious and potentially fatal conditions in immunocompromised patients.

The choice of Amphotericin B for Aspergillus fungal infections is crucial because these types of infections can be challenging to treat with other antifungal medications. Its broad spectrum activity allows healthcare providers to use Amphotericin B as a first-line treatment in serious fungal infections, especially in individuals with weakened immune systems.